missing translation for 'onlineSavingsMsg'
Learn More

Desmoglein Mouse, Unlabeled, Clone: 62, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 610273

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15825379

  • £241.00 / 1 set
Estimated Shipment: 02-05-2024
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Desmoglein (Dsg1) is a transmembrane glycoprotein found in desmosome junctions. Desmosomes and adherens junctions are plasma membrane specializations involved in cell-cell adhesion. They serve as membrane anchorage domains for intermediate filaments and microfilaments, respectively. Actin microfilaments anchor at adherens junctions, which occur in many sizes, shapes, and positions. These junctions generally contain E- or N-Cadherin whose cytoplasmic region is associated with cytoplasmic proteins such as α- and β- catenin, vinculin, α-actinin, and radixin. Intermediate filaments (IFs) are anchored at desmosomes which contain desmosome-specific cadherin family members, known as desmocollin (Dsc) and desmoglein. These proteins associate with cytoplasmic proteins such as desmoplakin and plakoglobin (γ-Catenin). Plakoglobin is the only junctional protein found at both desmosomes and adherens junctions and, therefore, plays a crucial role in cell adhesion.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

Desmoglein
Monoclonal
250μg/mL
Dsg1
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
Western Blot
62
Unconjugated
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
50 μg
Cell Biology
Canine, Chicken, Drosophila, Human, Mouse, Rat
IgG2b
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

For Research Use Only.