missing translation for 'onlineSavingsMsg'
Learn More

Cyclin D3 Mouse, Unlabeled, Clone: 1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 610280

Additional Details : Weight : 0.01100kg

 View more versions of this product

Product Code. 15865379

  • £343.55 / 1 set
Estimated Shipment: 21-12-2021

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Several classes of cyclins (A-E) have been described. These proteins act as regulatory subunits for cyclin-dependent kinases (cdks). The synthesis and degradation of cyclins is tightly controlled in a cell cycle specific manner. There are at least 3 different D-type cyclins whose relative levels vary among cell types. Cyclin D3 is known to associate with Cdk5 and weakly with Cdk2. Cdk4 is preferentially bound by Cyclin D1. However, in T cells which do not express Cyclin D1, Cdk4 associates with Cyclins D2 and D3. While bound to cdks, the D-type cyclins also associate with the polymerase-δ subunit, PCNA. Cyclin D3 has also been shown to bind pRb in vitro. This suggests that pRb may be an in vivo substrate of D-type cyclins.

This antibody is routinely tested by western blot analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Specifications

Specifications

Cyclin D3
1
Unconjugated
Affinity Purified
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
150μg
Cell Biology
Primary
Canine, Human, Murine, Rat
Western Blot
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Mouse
IgG2b
RUO
Store undiluted at -20°C.
Monoclonal
Videos
SDS
Documents
Certificates
Special Offers

Special Offers

For Research Use Only.