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CRF Polyclonal Antibody, Invitrogen™

CRF Antibody, PA1-28298, from Invitrogen™. Species Reactivity: Human, Mouse, Rat; Applications: Western Blot.

Brand:  Invitrogen PA1-28298

UNSPSC : 12352203

Code : LE

Additional Details : Weight : 0.01000kg

Product Code. 11585803

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance


Description

Description

Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin dificiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, CRH may act as a trigger for parturition.
Host Species: Chicken
Cross Reactivity: Human, Mouse, Rat
Isotype: IgY
Immunogen: Synthetic peptide, corresponding to amino acids 27-196 of Human Corticotrophin Releasing Factor CRF.
Formulation: 50μg purified antibody (1mg/mL) in PBS and no preservative
Synonyms: CRF
Uniprot Accession: P01143, P06850, Q8CIT0
Entrez GeneID: 12918, 1392, 81648
Gene Symbol: CRH
PA1-28298 detects CRF from mouse, rat, human samples. PA1-28298 has been successfully used in Western blot applications. Predicted molecular weight of 70kDa. The PA1-28298 immunogen is: Synthetic peptide, corresponding to amino acids 27-196 of Human Corticotrophin Releasing Factor CRF.
Specifications

Specifications

CRF
Polyclonal
50μg purified antibody (1mg/mL) in PBS and no preservative
Purified
CRH
Synthetic peptide, corresponding to amino acids 27-196 of Human Corticotrophin Releasing Factor CRF.
50μg
avoiding freeze/thaw cycles.
Primary
12918, 1392, 81648
Western Blot
Unlabeled
P01143, P06850, Q8CIT0
CRF
Chicken
IgY
RUO
Primary
Polyclonal
Rat