anti-CRF Polyclonal, Thermo Scientific™

CRF Polyclonal antibody PA1-28298 from Thermo Scientific™ specifically detects CRF in Human, Mouse and Rat samples, and it is validated for Western Blot

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-28298

CRF

UNSPSC: 12352203

Code: LE

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11585803

Quantity Price
1 £ 395.0 / 50µg
Estimated Shipment date
from Supplier 06-01-2017
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Description and Specification

Specification

Antigen CRF
Applications Western Blotting
Classification Polyclonal
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Purified
Formulation 50μg purified antibody (1mg/mL) in PBS and no preservative
Gene Accession No. P01143, P06850, Q8CIT0
Gene Alias CRF
Gene Symbols CRH
Host Species Chicken
Immunogen Synthetic peptide, corresponding to amino acids 27-196 of Human Corticotrophin Releasing Factor CRF.
Isotype IgY
Quantity 50μg
Regulatory Status RUO
Species Reactivity Human, Mouse, Rat
Storage Requirements avoiding freeze/thaw cycles.
Type Primary
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 12918, 1392, 81648

Corticotropin-releasing hormone (CRH) is a 41-amino acid peptide derived from a 191-amino acid preprohormone. CRH is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in CRH has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin dificiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, CRH is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta CRH is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of CRH occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, CRH may act as a trigger for parturition.
Host Species: Chicken
Cross Reactivity: Human, Mouse, Rat
Isotype: IgY
Immunogen: Synthetic peptide, corresponding to amino acids 27-196 of Human Corticotrophin Releasing Factor CRF.
Formulation: 50μg purified antibody (1mg/mL) in PBS and no preservative
Synonyms: CRF
Uniprot Accession: P01143, P06850, Q8CIT0
Entrez GeneID: 12918, 1392, 81648
Gene Symbol: CRH
PA1-28298 detects CRF from mouse, rat, human samples. PA1-28298 has been successfully used in Western blot applications. Predicted molecular weight of 70kDa. The PA1-28298 immunogen is: Synthetic peptide, corresponding to amino acids 27-196 of Human Corticotrophin Releasing Factor CRF.