CD42b Mouse anti-Human, Unlabeled, Clone: HIP1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 555471

Product Code. 15828198

Description

The HIP1 monoclonal antibody specifically binds to CD42b. CD42b is also known as the Platelet glycoprotein Ib alpha chain that is encoded by the GP1BA gene. CD42b is disulfide bonded to CD42c to form a 170 kDa heterodimer, GPIb. GPIb forms a noncovalent complex with CD42a and CD42d (CD42 complex) that is expressed on platelets and megakaryocytes. The CD42 complex serves as the von Willebrand Factor(vWF) surface receptor involved in the adhesion of platelets to the subendothelium of damaged vascular walls. HIP1 inhibits the ristocetin-dependent binding ofvWF to platelets and partially inhibits collagen-induced aggregation.

Specifications

• Antigen: CD42b
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C

• Applications: Flow Cytometry
• Clone: HIP1
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 0.1 mg
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.