CD3e Armenian Hamster anti-Mouse, PE-Cy7, Clone: 145-2C11, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-0031-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15340880

Quantity Price
1 £ 86.73 / 50µg
EU Stock 3
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Description and Specification

Specification

Applications Flow Cytometry
Cross Reactivity Mouse
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Regulatory Status RUO
Clone 145-2C11
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Gene Alias CD3 epsilon
Species Reactivity Mouse
Host Species Armenian Hamster
Conjugate PE-Cy7
Isotype IgG
Monoclonal or Polyclonal Monoclonal
Antigen CD3e
Quantity 50μg
Concentration 0.2mg/mL

The 145-2C11 monoclonal antibody reacts with mouse CD3e, a 20kDa subunit of the TCR complex. Along with the other CD3 subunits, gamma and delta, the epsilon chain is required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Binding of 145-2C11 to TCR initiates the intracellular biochemical pathway resulting in cellular activation, proliferation, and apoptosis depending on specific conditions utilized. 145-2C11 is commonly used as a phenotypic marker for mouse T cells.