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CD3 Mouse anti-Human, Clone: SK7, Functional Grade, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-0037-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15288347

  • £66.65 / 50µg


EU Stock 20
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Disclaimers:

For Research Use Only.


Description

Description

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.
Specifications

Specifications

CD3
OKT3
Unlabeled
Purified
Murine
50μg
Store at 2-8°C.
Monoclonal
Functional Assay
1mg/mL
aqueous buffer, no sodium azide
Leu-4, T3
IgG2a
RUO
Primary
Human