CD3 Mouse anti-Human, Clone: SK7, Functional Grade, eBioscience™

Mouse Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-0037-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15288347

Quantity Price
1 £ 66.65 / 50µg
EU Stock 18
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Description and Specification


Applications Flow Cytometry
Applications Functional Assay
Storage Requirements Store at 2-8°C.
Conjugate Unlabeled
Formulation aqueous buffer, no sodium azide
Regulatory Status RUO
Gene Alias Leu-4, T3
Primary or Secondary Primary
Species Reactivity Human
Isotype IgG2a
Cross Reactivity Human
Format Purified
Monoclonal or Polyclonal Monoclonal
Quantity 50μg
Antigen CD3
Clone OKT3
Concentration 1mg/mL
Host Species Mouse

The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. The OKT3 antibody has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. The CD3 subunits, gamma, delta, and epsilon chains, are required for proper assembly, trafficking and surface expression of the TCR complex. CD3 is expressed by thymocytes in a developmentally regulated manner and by all mature T cells. Crosslinking of TCR initiates an intracellular biochemical pathway resulting in cellular activation and proliferation.