CD16/FCGR3 Alexa Fluor 488 Monoclonal Antibody, Clone: 3G8, Invitrogen™
CD16/FCGR3 Antibody, Alexa Fluor 488 conjugate (3G8), MA5-18127, from Invitrogen™. Species Reactivity: Human, Non-human primate; Applications: Flow Cytometry.
Brand: Invitrogen MA518127
Code : NEW
Additional Details : Weight : 0.01000kg
DescriptionThis gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host Species: Mouse
Cross Reactivity: Human, Non-human primate
Immunogen: Human neutrophils
Formulation: 100 tests purified antibody in PBS with 0.2% BSA and 0.02% sodium azide
Synonyms: FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA
Uniprot Accession: O75015, P08637
Entrez GeneID: 2214, 2215
Gene Symbol: FCGR3A, FCGR3B
This product detects CD16/FCGR3 in Human and Non-human primate samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is Human neutrophils.
|100 tests purified antibody in PBS with 0.2% BSA and 0.02% sodium azide|
|Alexa Fluor™ 488|
|FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA|
|DO NOT FREEZE!|