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CD16/FCGR3 Alexa Fluor 647 Monoclonal Antibody, Clone: 3G8, Invitrogen™

CD16/FCGR3 Antibody, Alexa Fluor 647 conjugate (3G8), MA5-18128, from Invitrogen™. Species Reactivity: Human, Non-human primate; Applications: Flow Cytometry.

Brand:  Invitrogen MA518128

UNSPSC : 12352203

Code : NEW

Additional Details : Weight : 0.01000kg

Product Code. 15357394

  • £254.00 / 100 tests


Estimated Shipment
14-07-2017
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Specifications

Description

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Host Species: Mouse
Cross Reactivity: Human, Non-human primate
Isotype: IgG1
Clone: 3G8
Immunogen: Human neutrophils
Formulation: 100 tests purified antibody in PBS with 0.2% BSA and 15mM sodium azide
Synonyms: FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA
Uniprot Accession: O75015, P08637
Entrez GeneID: 2214, 2215
Gene Symbol: FCGR3A, FCGR3B
This product detects CD16/FCGR3 in Human and Non-human primate samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is Human neutrophils.
Description & Specifications

Specifications

CD16/FCGR3
3G8
Purified
O75015, P08637
FCGR3A, FCGR3B
Human neutrophils
100 Tests
Primary
2214, 2215
Flow Cytometry
Alexa Fluor 647
100 tests purified antibody in PBS with 0.2% BSA and 15mM sodium azide
FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA
Murine
IgG1
DO NOT FREEZE!
Monoclonal
Non-human Primate