CD11b (activation epitope) Mouse anti-Human, APC, Clone: CBRM1/5, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0114-82

100UG ANTI-MOUSE CD11C APC

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15320580

Quantity Price
1 £ 170.59 / 100µg
EU Stock 22
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Description and Specification

Specification

Gene Alias Integrin alpha X, Integrin aX, ITGAX, p150/95, leu M5 alpha
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Mouse
Regulatory Status RUO
Quantity 100μg
Cross Reactivity Mouse
Conjugate APC
Antigen CD11c
Clone N418
Primary or Secondary Primary
Host Species Armenian Hamster
Monoclonal or Polyclonal Monoclonal
Concentration 0.2mg/mL
Isotype IgG

The N418 monoclonal antibody reacts with mouse CD11c, the integrin αX. CD11c non-covalently associates with β2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90kDa heterodimer.