CD11b (activation epitope) Mouse anti-Human, APC, Clone: CBRM1/5, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 17-0114-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15320580

Quantity Price
1 £ 170.59 / 100µg
EU Stock 46
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Description and Specification

Specification

Conjugate Allophycocyanin
Gene Alias Integrin alpha X, Integrin aX, ITGAX, p150/95, leu M5 alpha
Applications Flow Cytometry
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Species Reactivity Mouse
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Format Conjugated
Regulatory Status RUO
Quantity 100μg
Cross Reactivity Mouse
Clone N418
Antigen CD11c
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Host Species Armenian Hamster
Concentration 0.2mg/mL
Isotype IgG

The N418 monoclonal antibody reacts with mouse CD11c, the integrin αX. CD11c non-covalently associates with β2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90kDa heterodimer.