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CD105 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA532303
Code : PN
Additional Details : Weight : 0.01000kg
Description
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil tissue.
CD105 or endoglin or GP160 is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists as an O- and N-glycosylated homodimer. Up-regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation-associated endothelial cell marker. CD105 binds to TGF-Beta1 and Beta3 with high affinity but not TGF-Beta2.Specifications
CD105 | |
Polyclonal | |
ENG | |
CD105, END, HHT1, ORW, ORW1, CD105 antigen, ENG | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
2022 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin) | |
Unconjugated | |
P17813 | |
ENG | |
Recombit protein encoding 26-176 aa of human CD105. | |
500 μL | |
Primary | |
Human | |
Antibody | |
IgG |