Amyloid beta A4 Polyclonal Antibody, Invitrogen™

Amyloid beta A4 Antibody, PA1-18318, from Invitrogen™. Species Reactivity: Rat; Applications: Immunohistochemistry.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-18318

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11591982

Quantity Price
1 £ 245.0 / 100µL
Estimated Shipment date
from Supplier 25-04-2017
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Description and Specification

Specification

Gene ID (Entrez) 54226
Gene Symbols APP
Formulation 100μL unpurified antibody in whole serum and no preservative
Antigen Amyloid beta A4
Storage Requirements Avoid Freeze/Thaw Cycles
Cross Reactivity Rat
Immunogen Synthetic peptide corresponding to residues H(44) M N V Q N G K W E S D P S G T K T C(62) of mouse APP isoform A.
Isotype IgG
Primary or Secondary Primary
Format Serum
Gene Accession No. P08592
Host Species Rabbit
Conjugate Unlabeled
Species Reactivity Rat
Monoclonal or Polyclonal Polyclonal
Quantity 100μL
Applications Immunohistochemistry
Gene Alias APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1

APP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. The APP protein is involved in cell mobility and transcription regulation through protein-protein interactions. APP can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. APP couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
Host Species: Rabbit
Cross Reactivity: Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues H(44) M N V Q N G K W E S D P S G T K T C(62) of mouse APP isoform A.
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
Uniprot Accession: P08592
Entrez GeneID: 54226
Gene Symbol: APP
PA1-18318 detects APP from rat samples. PA1-18318 has been successfully used in immunohistochemistry procedures. The PA1-18318 immunogen is a synthetic peptide corresponding to residues H(44) M N V Q N G K W E S D P S G T K T C(62) of mouse APP isoform A, conjugated to Blue Carrier Protein. Reconstitute with 100 ul of distilled water.