anti-Amyloid beta A4 Polyclonal, Thermo Scientific™

Amyloid beta A4 Polyclonal antibody PA1-18317 from Thermo Scientific™ specifically detects Amyloid beta A4 in Rat samples, and it is validated for Immunohistochemistry

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-18317

AMYLOID BETA A4

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11581982

Quantity Price
1 £ 245.0 / 100µL
Estimated Shipment date
from Supplier 16-02-2017
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Description and Specification

Specification

Formulation 100μL unpurified antibody in whole serum and no preservative
Gene Symbols APP
Immunogen C-H(388) A H F Q K A K E R L E A K H R E R(405)
Gene ID (Entrez) 54226
Antigen Amyloid beta A4
Storage Requirements Avoid Freeze/Thaw Cycles
Cross Reactivity Rat
Isotype IgG
Primary or Secondary Primary
Format Serum
Gene Accession No. P08592
Host Species Rabbit
Species Reactivity Rat
Conjugate Unlabeled
Quantity 100μL
Monoclonal or Polyclonal Polyclonal
Gene Alias APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
Applications Immunohistochemistry

APP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. The APP protein is involved in cell mobility and transcription regulation through protein-protein interactions. APP can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. APP couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
Host Species: Rabbit
Cross Reactivity: Rat
Isotype: IgG
Immunogen: Synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
Uniprot Accession: P08592
Entrez GeneID: 54226
Gene Symbol: APP
PA1-18317 detects APP from rat samples. PA1-18317 has been successfully used in immunohistochemistry procedures. The PA1-18317 immunogen is a synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K Q Y T S I H H G V V E(737) of human APP isoform A, conjugated to KLH. Reconstitute with 100 ul of distilled water.