Amyloid beta A4 Polyclonal Antibody, Invitrogen™
Amyloid beta A4 Antibody, PA1-18317, from Invitrogen™. Species Reactivity: Rat; Applications: Immunohistochemistry.
Brand: Invitrogen PA118317
Code : LD
Additional Details : Weight : 0.01000kg
DescriptionAPP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. The APP protein is involved in cell mobility and transcription regulation through protein-protein interactions. APP can promote transcription activation through binding to APBB1/Tip60 and inhibit Notch signaling through interaction with Numb. APP couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1.
Host Species: Rabbit
Cross Reactivity: Rat
Immunogen: Synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1
Uniprot Accession: P08592
Entrez GeneID: 54226
Gene Symbol: APP
PA1-18317 detects APP from rat samples. PA1-18317 has been successfully used in immunohistochemistry procedures. The PA1-18317 immunogen is a synthetic peptides corresponding to residuess C-E(145) T H L H W H T V A K E T(157), C-H(388) A H F Q K A K E R L E A K H R E R(405), and C-K(724) K K Q Y T S I H H G V V E(737) of human APP isoform A, conjugated to KLH. Reconstitute with 100 ul of distilled water.
|Amyloid beta A4|
|APP, ABPP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP; Protease nexin-II, PN-II, APPI, PreA4, A4, AD1|
|Avoid Freeze/Thaw Cycles|
|100μL unpurified antibody in whole serum and no preservative|
|C-H(388) A H F Q K A K E R L E A K H R E R(405)|