eBioscience™ Human M-CSF, Recombinant Protein, Carrier-Free

Human Recombinant Protein

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 34-8789-85

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Product Code. 15538836

Quantity Price
1 £ 1020.44 / 500µg
Estimated Shipment date
from Supplier 05-06-2017
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Description and Specification

Specification

Conjugate Unlabeled
Cross Reactivity Human
Formulation Sterile liquid: phosphate-buffered saline, 0.22μm filtered
Quantity 500μg
Storage Requirements Store at less than or equal to -70°C.
Purification Method SDS-PAGE
Endotoxin Concentration Less than 0.01ng/μg cytokine as determined by the LAL assay.
Molecular Weight 36kDa
Regulatory Status RUO
Product Type Recombinant Protein, Carrier-Free
Purity >95%
Source Insect Cells
Structural Form Human M-CSF Glu34-Ser190 accession number NM-172211 expressed in insect cells with a C-terminal 6X His tag.
For Use With (Application) Cytokine Bioassays
Biological Activity The bioactivity of this protein, as determined in a cell proliferation assay on M-NFS-60 cells, is 3ng/mL. This corresponds to a specific activity of 3.3 X 105 Units/mg.
Recombinant Yes
Accession Number NM-172211
Name M-CSF
Gene Symbol CSF1, Macrophage colony-stimulating factor 1
Macrophage colony stimulating factor, monocyte colony stimulating factor

Human Macrophage Colony Stimulating Factor (M-CSF, also called CSF-1) is a ∽36 kDa disulfide-linked homodimer produced by a variety of cells including fibroblasts, macrophages, bone marrow stromal cells and endothelial cells. M-CSF regulates macrophage survival, proliferation and differentiation. M-CSF also enhances macrophage killing of tumor cells and microorganisms and regulates cytokine production from macrophages.