Angiogenin Mouse anti-Human, Clone: 26-2F, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-9762-82
Code : NEW
Additional Details : Weight : 0.09500kg
DescriptionApplications Reported: This 26-2F antibody has been reported for use in cytokine neutralization, immunoprecipitation, immunohistochemical staining of frozen tissue sections, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, ELISA, and immunocytochemistry. Applications Tested: This 26-2F antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using low or high pH antigen retrieval and can be used at less than or equal to 20 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.
|PBS with 0.09% sodium azide; pH 7.2|
|ALS9, HEL168, MGC22466, MGC71966, RNASE4, RNASE5|
|ELISA, Functional Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Neutralization|
For Research Use Only.