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AMN 082 dihydrochloride, Tocris Bioscience™

The first selective mGlu7 agonist

Brand:  Tocris (Bio-Techne) 238510

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13461114

  • £114.00 / 10mg


Estimated Shipment
31-08-2018
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Description

Description

The first selective mGlu7 agonist. Potently inhibits cAMP accumulation and stimulates GTPγS binding in recombinant cells and on membranes expressing mGlu7 (EC50 = 64 - 290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μM. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats.
Specifications

Chemical Identifiers

97075-46-2
465.462
N, N'-Bis(diphenylmethyl)-1, 2-ethanediamine dihydrochloride
C28H30Cl2N2
YRQCDCNQANSUPB-UHFFFAOYSA-N
11698390

Specifications

AMN 082 dihydrochloride
>99%
N, N'-Bis(diphenylmethyl)-1, 2-ethanediamine dihydrochloride
C1=CC=C(C=C1)C(C2=CC=CC=C2)NCCNC(C3=CC=CC=C3)C4=CC=CC=C4.Cl.Cl
465.462
10mg
97075-46-2
C28H30Cl2N2
YRQCDCNQANSUPB-UHFFFAOYSA-N
N,N'-dibenzhydrylethane-1,2-diamine;dihydrochloride
11698390
465.45
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