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  8. Aluminon, ACS, Thermo Scientific Chemicals

Aluminon, ACS, Thermo Scientific Chemicals

Catalog Number p-7050229
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Quantity:
25 g
100 g
This item is not returnable. View return policy
569-58-4
C22H23N3O9
473.438
MFCD00040925
AIPNSHNRCQOTRI-UHFFFAOYSA-N
aluminon, ammonium aurintricarboxylate, aurintricarboxylic acid ammonium salt, aurintricarboxylic acid, acs
54729869
CHEBI:87398
triazanium;5-[(3-carboxy-4-oxidophenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-oxidobenzoate
C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]
This item is not returnable. View return policy
569-58-4
C22H23N3O9
473.438
MFCD00040925
AIPNSHNRCQOTRI-UHFFFAOYSA-N
aluminon, ammonium aurintricarboxylate, aurintricarboxylic acid ammonium salt, aurintricarboxylic acid, acs
54729869
CHEBI:87398
triazanium;5-[(3-carboxy-4-oxidophenyl)-(3-carboxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-oxidobenzoate
C1=CC(=C(C=C1C(=C2C=CC(=O)C(=C2)C(=O)O)C3=CC(=C(C=C3)[O-])C(=O)[O-])C(=O)O)[O-].[NH4+].[NH4+].[NH4+]

Description

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca2+ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca2+-activated protease that is activated during apoptosis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY
Melting Point 220°C to 225°C (decomposition)
pH 5.3
Odor Odorless
Quantity 25 g
Merck Index 14,322
Solubility Information Soluble in water(800g/L).
Formula Weight 473.44
Grade ACS
Physical Form Powder
Chemical Name or Material Aluminon

Safety and Handling

compliance-icons
Product Identifier
  • Aluminon
 Signal Word
  • Warning
 Hazard Category
  • Skin corrosion/irritation Category 2
  • Serious eye damage/eye irritation Category 2
 Hazard Statement
  • H315-Causes skin irritation.
  • H319-Causes serious eye irritation.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P321-Specific treatment (see on this label).
  • P332+P313-If skin irritation occurs: Get medical advice/attention.
  • P362-Take off contaminated clothing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P337+P313-If eye irritation persists: Get medical advice/attention.

RUO – Research Use Only

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