alpha GalCer:CD1d complex Mouse anti-Mouse, PE, Clone: L363, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 12-2019-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15238719

Quantity Price
1 £ 60.53 / 25µg
EU Stock 1
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Description and Specification

Specification

Monoclonal or Polyclonal Monoclonal
Format Conjugated
Host Species Mouse
Gene Alias alpha GalCer-CD1d complex, alphaGalCerCD1d complex, alpha galcer-CD1d complex, alpha-galactosylceramide, alpha galactosylceramide, CD1d
Quantity 25μg
Clone L363
Isotype IgG2a
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Mouse
Applications Flow Cytometry
Conjugate PE
Antigen alpha GalCer:CD1d complex
Regulatory Status RUO
Concentration 0.2mg/mL

This L363 monoclonal antibody reacts with α-galactosylceramide bound to the mouse MHC class I-like protein CD1d. This complex is recognized by invariant natural killer T (iNKT) cells, a subset of T lymphocytes that expresses the invariant TCR α chain Vα14Jα18. Activation of iNKT cells leads to production of Th1 and Th2-associated cytokines as well as dendritic cell maturation.

The L363 antibody has been reported to neutralize iNKT cell activation by α-galactosylceramide:CD1d complexes.