alpha GalCer:CD1d complex Mouse anti-Mouse, Clone: L363, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-2019-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15208597

Quantity Price
1 £ 103.33 / 100µg
EU Stock 1
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Description and Specification

Specification

Host Species Murine
Formulation aqueous buffer, no sodium azide
Primary or Secondary Primary
Antigen alpha GalCer:CD1d complex
Conjugate Unlabeled
Isotype IgG2a
Applications Flow Cytometry
Applications Functional Assay
Concentration 1mg/mL
Clone L363
Monoclonal or Polyclonal Monoclonal
Quantity 100μg
Format Purified
Regulatory Status RUO
Storage Requirements Store at 2-8°C.
Species Reactivity Mouse
Gene Alias alpha GalCer-CD1d complex

This L363 monoclonal antibody reacts with α-galactosylceramide bound to the mouse MHC class I-like protein CD1d. This complex is recognized by invariant natural killer T (iNKT) cells, a subset of T lymphocytes that expresses the invariant TCR α chain Vα14Jα18. Activation of iNKT cells leads to production of Th1 and Th2-associated cytokines as well as dendritic cell maturation.

The L363 antibody has been reported to neutralize iNKT cell activation by α-galactosylceramide:CD1d complexes.