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alpha GalCer:CD1d Complex, Functional Grade, clone: L363, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-2019-80

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15298587

  • £56.31 / 25µg


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Description

Description

Description: This L363 monoclonal antibody reacts with alpha-galactosylceramide bound to the mouse MHC class I-like protein CD1d. This complex is recognized by invariant natural killer T (iNKT) cells, a subset of T lymphocytes that expresses the invariant TCR alpha chain Valpha14Jalpha18. Activation of iNKT cells leads to production of Th1 and Th2-associated cytokines as well as dendritic cell maturation.The L363 antibody has been reported to neutralize iNKT cell activation by alpha-galactosylceramide:CD1d complexes.Applications Reported: This L363 antibody has been reported for use in functional assays.Applications Tested: This L363 antibody has been tested by flow cytometric analysis of alpha-galactosylcermide-loaded mouse CD1d-transfected cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay.Storage and handling: Use in a sterile environment.Filtration: 0.2μm post-manufacturing filtered.Purity: Greater than 90%, as determined by SDS-PAGE.Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay.Aggregation: Less than 10%, as determined by HPLC.
Specifications

Specifications

alpha GalCer:CD1d complex
Monoclonal
1mg/mL
PBS with no preservative; pH 7.2
P11609
alpha GalCer-CD1d complex
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Functional Assay
L363
Functional Grade
Cd1d1
Purified
Cd1d1
IgG2a, kappa
25μg
Store at 2-8°C.
Primary
12479
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