alpha GalCer:CD1d complex Mouse anti-Mouse, Clone: L363, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-2019-80

25UG:ANTI-MOUSE ALPHA GALCER:CD1D COMPLEX

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15298587

Quantity Price
1 £ 82.0 / 25µg
Estimated Shipment date
from Supplier 13-12-2016
Add to basket


Description and Specification

Specification

Antigen alpha GalCer:CD1d complex
Applications Flow Cytometry
Applications Functional Assay
Clone L363
Concentration 1mg/mL
Conjugate Unlabeled
Format Purified
Formulation aqueous buffer, no sodium azide
Gene Alias alpha GalCer-CD1d complex
Host Species Mouse
Isotype IgG2a
Quantity 25μg
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal

This L363 monoclonal antibody reacts with α-galactosylceramide bound to the mouse MHC class I-like protein CD1d. This complex is recognized by invariant natural killer T (iNKT) cells, a subset of T lymphocytes that expresses the invariant TCR α chain Vα14Jα18. Activation of iNKT cells leads to production of Th1 and Th2-associated cytokines as well as dendritic cell maturation.

The L363 antibody has been reported to neutralize iNKT cell activation by α-galactosylceramide:CD1d complexes.