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Alpha Catenin Mouse anti-Human, Clone: 1G5, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9120-82

Code : NEW

Additional Details : Weight : 0.09500kg

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Product Code. 15547586

This item has been discontinued and is no longer available. View the product for possible alternatives or contact our Product Support team on 01509 555888 for assistance

Disclaimers:

For Research Use Only.


Specifications

Description

The monoclonal antibody 1G5 recognizes human alpha catenin. Alpha catenin plays a role in cell-cell adhesion through its function in the binding and bundling of actin. The N-terminus of alpha catenin binds beta catenin and the C-terminus binds actin. Monomeric alpha catenin acts as a physical linker between the cadherin-beta catenin complex and the actin cytoskeleton and is stabilized by dimeric alpha catenin found in the cytoplasm. Alpha catenin also binds other actin-related proteins, including vinculin, alpha-actinin, ZO-1, afadin, formin-1, and Rho. Alpha catenin is absent in some tumor cell lines and reduced in some human carcinomas.
Description & Specifications

Specifications

Alpha Catenin
1G5
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
IgG1
RUO
Primary
Human
Western Blot
0.5mg/mL
Purified
Murine
100μg
Store at 2-8°C.
Monoclonal