missing translation for 'onlineSavingsMsg'
Learn More

AHR Monoclonal Antibody (4MEJJ), eFluor™ 660, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-5925-80

92.00 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Code : NEW

Additional Details : Weight : 0.09500kg

 View more versions of this product

Product Code. 15599986

  • £138.00 / 25µg
Estimated Shipment: 07-05-2024
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

Description: This 4MEJJ monoclonal antibody recognizes mouse aryl hydrocarbon receptor (AHR). The AHR is a ligand-activated transcription factor that mediates the toxic effects of a diverse group of environmental contamits, most notably aryl hydrocarbons such as polychlorinated biphenyls (PCB) and tetrachlorodibenzo-p-dioxin (TCDD). The AHR has also been shown to bind to a number of naturally occurring compounds found in fruits and vegetables as well as compounds generated through normal cellular metabolism. AHR is localized in the cytoplasm in a complex that includes HSP90, p23, and XAP2/AIP/ARA9. Upon ligand-binding, AHR translocates to the nucleus and binds with aryl hydrocarbon receptor nuclear translocator (ARNT), and this complex binds to the consensus DNA sequence, GCGTG, found in the promoter/enhancer regions of many genes such as CYP1A1. The AHR is expressed in many cell types, with highest expression levels found in liver. The AHR has been shown to play a role in the regulation/differentiation of Treg and Th17 cells. The 4MEJJ monoclonal antibody has been found to recognize the b-1, b-2 and d alleles of mouse AHR but does not crossreact with human AHR. Applications Reported: This 4MEJJ antibody has been reported for use in intracellular staining followed by flow cytometric analysis.

AHR Monoclonal antibody specifically detects AHR in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

AHR
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P30561
AHR
E. coli derived, His-tagged AHR (aa 443-805)
25 μg
Primary
Mouse
Antibody
IgG2a κ
Flow Cytometry
4MEJJ
eFluor 660
AHR
Ah; Ah receptor; Ahh; Ahr; Ahre; AH-receptor; aromatic hydrocarbon receptor; aryl hydrocarbon receptor; aryl-hydrocarbon receptor; bHLHe76; Class E basic helix-loop-helix protein 76; dioxin receptor; In
Rat
Affinity chromatography
RUO
11622
4° C, store in dark, DO NOT FREEZE!
Liquid
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

For Research Use Only.