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AHNAK Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA553912

Additional Details : Weight : 0.02000kg

Product Code. 15711851

  • £340.00 / 100µL

Estimated Shipment
10-12-2020

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Description

Description

AHNAK1 (Desmoyokin) is a large (700 kDa) scaffold protein that translocates to the plasma membrane after an increas of extracellular calcium level or upon proteinkinase C activation and regulates extracellular calcium influx mediated by L-type Ca2+ channels. AHNAK1 has been implicated in diverse signal transduction proceses affecting cell differentiation and proliferation. In response to calcium-dependent intercellular contacts AHNAK1 forms multimeric complexes in the plasma membrane, connected with actin and annexin 2/S100A10 assemblies and is thus involved in organization of the plasma membrane architecture. In epithelial cells, AHNAK1 is localized in cytoplasm or is membrane-associated, but in cells of nonepithelial origin AHNAK1 is predomitly nuclear; it has a weak DNA-binding activity and associates with the DNA-ligase IV-XRCC4 complex.
Specifications

Specifications

AHNAK
Polyclonal
Unconjugated
AHNAK
Liquid
AHNAK
Recombit protein corresponding to Human AHNAK
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q09666
AHNAKRS, MGC5395, AHNAK-related, desmoyokin, neuroblast differentiation-associated protein AHNAK
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
79026
Videos
SDS
Documents

Research Use Only