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alpha-Fetoprotein Mouse anti-Human, Clone: 1E8, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9499-82

Code : NEW

Additional Details : Weight : 0.09500kg

Product Code. 15587596

  • £301.00 / 100µg

Estimated Shipment
17-08-2020

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Description

Description

AFP (Alpha Fetoprotein) is a major plasma protein produced by the yolk sac, intestinal tract and the liver during fetal life. AFP expression in adults is often associated with hepatoma or teratoma. However, hereditary persistence of AFP may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and AFP and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. AFP is found in monomeric, dimeric, and trimeric forms. AFP can also bind to copper ions, nickel ions, fatty acids and bilirubin. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. High level of serum AFP has been identified in patients with hepatocellular carcinomas (HCC), teratoblastoma, colorectal cancer, pancreatic cancer, and germ cell neoplasms.
Specifications

Specifications

alpha-Fetoprotein
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P02771
alpha-fetoglobulin, alpha-1-fetoprotein, AFP
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1E8
Unconjugated
AFP
Liquid
AFP
IgG1, kappa
100 μg
4° C
Primary
174
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