AFP Mouse anti-Human, Clone: 1E8, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-9499-82

Code: NEW

Additional Details:
Additional Details: Weight: 0.09500kg



Disclaimers: For Research Use Only.

Product Code. 15587596

Quantity Price
1 £ 182.82 / 100µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Gene Alias AFP
Primary or Secondary Primary
Applications Immunocytochemistry
Applications Immunohistochemistry (Formalin/Paraffin)
Applications Western Blotting
Format Purified
Regulatory Status RUO
Clone 1.00E+08
Isotype IgG1
Species Reactivity Human
Quantity 100μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen AFP
Concentration 0.5mg/mL
Monoclonal or Polyclonal Monoclonal
Conjugate Unlabeled
Host Species Mouse
Storage Requirements Store at 2-8°C.

This 1E8 monoclonal antibody reacts with human alpha-fetoprotein (AFP). This 70kDa secretory protein is a member of the albumin gene family. Synthesized by the yolk sac and fetal liver during embryogenesis, AFP protein levels are highest in fetal serum. After birth, serum AFP levels decrease dramatically. In fact, AFP is nearly undetectable in normal adult serum. However, hepatocellular carcinoma and germ cell teratoblastoma, as well as liver regeneration, viral hepatitis, and cirrhosis, leads to elevated AFP serum levels in adults. As such, detection of this protein is frequently used as a diagnostic marker for these conditions.