AFP Mouse anti-Human, Alexa Fluor 488, Clone: AFP3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-6583-80

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15362060

Quantity Price
1 £ 111.78 / 25µg
EU Stock 1
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Description and Specification

Specification

Gene Alias AFP
Host Species Mouse
Isotype IgG1
Concentration 0.5mg/mL
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Conjugate Alexa Fluor 488
Antigen AFP
Species Reactivity Human
Applications Immunocytochemistry
Primary or Secondary Primary
Quantity 25μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Monoclonal or Polyclonal Monoclonal
Regulatory Status RUO
Clone AFP3
Format Conjugated

This AFP3 monoclonal antibody reacts with human alpha-fetoprotein (AFP). This 70kDa secretory protein is a member of the albumin gene family. Synthesized by the yolk sac and fetal liver during embryogenesis, AFP protein levels are highest in fetal serum. After birth, serum AFP levels decrease dramatically. In fact, AFP is nearly undetectable in normal adult serum. However, hepatocellular carcinoma and germ cell teratoblastoma, as well as liver regeneration, viral hepatitis, and cirrhosis, leads to elevated AFP serum levels in adults. As such, detection of this protein is frequently used as a diagnostic marker for these conditions.
When performing western blotting or immunohistochemistry on paraffin section, we recommend the use of monoclonal antibody 1E8 (cat. 14-9499).