AFP Mouse anti-Human, Alexa Fluor 488, Clone: AFP3, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-6583-82

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15372060

Quantity Price
1 £ 211.35 / 100µg
Estimated Shipment date
from Supplier 05-05-2017
Add to basket


Description and Specification

Specification

Host Species Murine
Applications Immunocytochemistry
Species Reactivity Human
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Quantity 100μg
Conjugate Alexa Fluor 488
Format Conjugated
Isotype IgG1
Gene Alias AFP
Regulatory Status RUO
Monoclonal or Polyclonal Monoclonal
Clone AFP3
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen AFP
Primary or Secondary Primary

This AFP3 monoclonal antibody reacts with human alpha-fetoprotein (AFP). This 70kDa secretory protein is a member of the albumin gene family. Synthesized by the yolk sac and fetal liver during embryogenesis, AFP protein levels are highest in fetal serum. After birth, serum AFP levels decrease dramatically. In fact, AFP is nearly undetectable in normal adult serum. However, hepatocellular carcinoma and germ cell teratoblastoma, as well as liver regeneration, viral hepatitis, and cirrhosis, leads to elevated AFP serum levels in adults. As such, detection of this protein is frequently used as a diagnostic marker for these conditions.
When performing western blotting or immunohistochemistry on paraffin section, we recommend the use of monoclonal antibody 1E8 (cat. 14-9499).