AFP Mouse anti-Human, Alexa Fluor 488, Clone: AFP3, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 53-6583-82
UNSPSC : 12352200
Code : Z2
Additional Details : Weight : 0.25000kg
DescriptionThis AFP3 monoclonal antibody reacts with human alpha-fetoprotein (AFP). This 70kDa secretory protein is a member of the albumin gene family. Synthesized by the yolk sac and fetal liver during embryogenesis, AFP protein levels are highest in fetal serum. After birth, serum AFP levels decrease dramatically. In fact, AFP is nearly undetectable in normal adult serum. However, hepatocellular carcinoma and germ cell teratoblastoma, as well as liver regeneration, viral hepatitis, and cirrhosis, leads to elevated AFP serum levels in adults. As such, detection of this protein is frequently used as a diagnostic marker for these conditions.
When performing western blotting or immunohistochemistry on paraffin section, we recommend the use of monoclonal antibody 1E8 (cat. 14-9499).
|Alexa Fluor 488|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|