Alfa Aesar™ Actinomycin D
Brand: Alfa Aesar™ J60148.#0
Code : NEW
Additional Details : CAS Number : 50-76-0 Weight : 0.00005kg Transport : UN number : 3462 Chem class : 1 Pack group : III
Actinomycin D is used as an anti-neoplastic antibiotic. It is also used to inhibit RNA polymerase and is a potent inducer of apoptosis. It is also used as a potent antibiotic that binds to the GpC steps of DNA. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells.
It is soluble ino 50 mM in DMSO.
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
|Dactinomycin; Actinomycin C1|
|251° to 253°C|
|Orange to red|