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Alfa Aesar™ Actinomycin D

Brand:  Alfa Aesar™ J60148.#0

Code : NEW

Additional Details : CAS Number : 50-76-0 Weight : 0.00005kg Transport : UN number : 3462 Chem class : 1 Pack group : III

Product Code. 15452969

  • £71.76 / 5mg


Estimated Shipment date
from Supplier 16-11-2017
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Description

Description

Applications
Actinomycin D is used as an anti-neoplastic antibiotic. It is also used to inhibit RNA polymerase and is a potent inducer of apoptosis. It is also used as a potent antibiotic that binds to the GpC steps of DNA. Inhibits DNA-primed RNA polymerase by complexing with DNA via deoxyguanosine residues. A DNA-intercalator with growth inhibitory activity against certain leukemias and sarcomas. At higher concentrations, DNA polymerase is inhibited. Inhibits cell growth and colony formation in synchronized HeLa cells.

Solubility
It is soluble ino 50 mM in DMSO.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Specifications

Specifications

Actinomycin D
Powder
MFCD00005033
605235
Dactinomycin; Actinomycin C1
251° to 253°C
50-76-0
1255.4
UN3462
14,2800
Orange to red
5mg
Documentation

Technical Documents