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AC 55541, Tocris Bioscience™

Potent and selective PAR2 agonist

Brand:  Tocris (Bio-Techne) 336910

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13442904

  • £188.76 / 10mg

Estimated Shipment date
from Supplier 24-09-2019

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Description

Description

Potent and selective protease-activated receptor 2 (PAR2) agonist (pEC50 = 6.7) that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation. Stimulates cell proliferation, PI hydrolysis and Ca2+ mobilization in vitro (pEC50 values are 6.7, 5.9 and 6.6 respectively) and exhibits pronociceptive activity in vivo.
Specifications

Chemical Identifiers

916170-19-9
518.371
ac hplc , powder, 2e-2-1-3-bromophenyl ethylidene ?-benzoylamino-3,4-dihydro-4-oxo-1-phthalazineacetic acid hydrazide, e-n-2-2-1-3-bromophenyl ethylidene hydrazinyl-2-oxo-1-4-oxo-3,4-dihydrophthalazin-1-yl ethyl benzamide, n-n'-1e-1-3-bromophenyl ethylidene hydrazinecarbonyl 4-oxo-3,4-dihydrophthalazin-1-yl methyl benzamide
N-[2-[(2E)-2-[1-(3-bromophenyl)ethylidene]hydrazinyl]-2-oxo-1-(4-oxo-3H-phthalazin-1-yl)ethyl]benzamide
C25H20BrN5O3
UCUHFWIFSHROPY-RWPZCVJISA-N
9589606
CC(=NNC(=O)C(C1=NNC(=O)C2=CC=CC=C21)NC(=O)C3=CC=CC=C3)C4=CC(=CC=C4)Br

Specifications

AC 55541
916170-19-9
ac hplc , powder, 2e-2-1-3-bromophenyl ethylidene ?-benzoylamino-3,4-dihydro-4-oxo-1-phthalazineacetic acid hydrazide, e-n-2-2-1-3-bromophenyl ethylidene hydrazinyl-2-oxo-1-4-oxo-3,4-dihydrophthalazin-1-yl ethyl benzamide, n-n'-1e-1-3-bromophenyl ethylidene hydrazinecarbonyl 4-oxo-3,4-dihydrophthalazin-1-yl methyl benzamide
CC(=NNC(=O)C(C1=NNC(=O)C2=CC=CC=C21)NC(=O)C3=CC=CC=C3)C4=CC(=CC=C4)Br
518.371
518.36
10mg
C25H20BrN5O3
UCUHFWIFSHROPY-RWPZCVJISA-N
N-[2-[(2E)-2-[1-(3-bromophenyl)ethylidene]hydrazinyl]-2-oxo-1-(4-oxo-3H-phthalazin-1-yl)ethyl]benzamide
9589606
>97%
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