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A 438079 hydrochloride, Tocris Bioscience™

Competitive P2X7 antagonist

Brand:  Tocris (Bio-Techne) 297250

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13462164

  • £608.00 / 50mg


Estimated Shipment
05-07-2018
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Description

Description

Competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 >> 10 μM). Possesses antinociceptive activity in models of neuropathic pain in vivo. Inhibits methamphetamine-induced microglial migration and phagocytosis in vitro.
Specifications

Chemical Identifiers

A 438079 hydrochloride
C13H9Cl2N5·HCl
342.61
3-[[5-(2, 3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride

Specifications

A 438079 hydrochloride
899431-18-6
C13H9Cl2N5·HCl
3-[[5-(2, 3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride
50mg
>98%
342.61
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