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4μ8C, Tocris Bioscience™

Inhibits IRE1α endoribonuclease activity

£196.98 - £764.40

Chemical Identifiers

CAS 14003-96-4
Molecular Formula C11H8O4
Molecular Weight (g/mol) 204.181
InChI Key RTHHSXOVIJWFQP-UHFFFAOYSA-N
Synonym 7-hydroxy-4-methyl-2-oxo-2h-chromene-8-carbaldehyde, 4mu8c, 8-formyl-7-hydroxy-4-methylcoumarin, 2h-1-benzopyran-8-carboxaldehyde, 7-hydroxy-4-methyl-2-oxo, 4micro8c, 8-formyl-7-hydroxy-4-methyl-coumarin, 7-hydroxy-4-methyl-2-oxo-2h-1-benzopyran-8-carbaldehyde, 7-hydroxy-4-methyl-2-oxo-2h-1-benzopyran-8-carboxaldehyde
PubChem CID 12934390
IUPAC Name 7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
SMILES CC1=CC(=O)OC2=C1C=CC(=C2C=O)O
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
13454814 View Documents RD Systems (Bio-Techne)
4479/10
10mg £196.98
10mg View alternative products
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Estimated Shipment date
from Supplier 01-04-2020
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13464814 View Documents Tocris (Bio-Techne)
447950
50mg £764.40
50mg View alternative products
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Estimated Shipment date
from Supplier 01-04-2020
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Description

Description

Selective inhibitor of IRE1α ribonuclease (RNase) activity (IC50 = 60 nM). Blocks substrate access to the active site of IRE1α. Inactivates IRE1α-mediated mRNA degradation. Displays no effect on the IRE1α-related endoribonuclease RNase L.
Specifications

Chemical Identifiers

14003-96-4
204.181
7-hydroxy-4-methyl-2-oxo-2h-chromene-8-carbaldehyde, 4mu8c, 8-formyl-7-hydroxy-4-methylcoumarin, 2h-1-benzopyran-8-carboxaldehyde, 7-hydroxy-4-methyl-2-oxo, 4micro8c, 8-formyl-7-hydroxy-4-methyl-coumarin, 7-hydroxy-4-methyl-2-oxo-2h-1-benzopyran-8-carbaldehyde, 7-hydroxy-4-methyl-2-oxo-2h-1-benzopyran-8-carboxaldehyde
7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
C11H8O4
RTHHSXOVIJWFQP-UHFFFAOYSA-N
12934390
CC1=CC(=O)OC2=C1C=CC(=C2C=O)O

Specifications

10mg
14003-96-4
7-hydroxy-4-methyl-2-oxo-2h-chromene-8-carbaldehyde, 4mu8c, 8-formyl-7-hydroxy-4-methylcoumarin, 2h-1-benzopyran-8-carboxaldehyde, 7-hydroxy-4-methyl-2-oxo, 4micro8c, 8-formyl-7-hydroxy-4-methyl-coumarin, 7-hydroxy-4-methyl-2-oxo-2h-1-benzopyran-8-carbaldehyde, 7-hydroxy-4-methyl-2-oxo-2h-1-benzopyran-8-carboxaldehyde
CC1=CC(=O)OC2=C1C=CC(=C2C=O)O
204.181
204.18
4μ8C
C11H8O4
RTHHSXOVIJWFQP-UHFFFAOYSA-N
7-hydroxy-4-methyl-2-oxochromene-8-carbaldehyde
12934390
>98%