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3G11 Sialoganglioside Antigen Monoclonal Antibody (eBio3G11 (SM3G11, 3G11)), eFluor™ 660, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
£90.75 - £232.00
Specifications
Antigen | 3G11 Sialoganglioside Antigen |
---|---|
Clone | eBio3G11 (SM3G11, 3G11), 3G11) |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15519976
|
Affymetrix eBioscience
50-5443-80 |
25 μg |
£90.75
25µg |
Estimated Shipment: 29-05-2024 Log in to see stock. |
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15529976
|
Affymetrix eBioscience
50-5443-82 |
100 μg |
£232.00
100µg |
Estimated Shipment: 29-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The 3G11 sialylated carbohydrate antigen was found to be expressed by thymoyctes and peripheral T cells, but not by B cells, myeloid cells or erythrocytes. 3G11 is expressed at higher levels on CD4+ T cells than on CD8+ T cells, however expression on both of these subsets decreases with advancing age. In thymus, 3G11 is expressed on approximately 20% of total thymocytes. 3G11 has also been used as a marker to distinguish naive and memory T cells, as 3G11 is irreversibly down-regulated upon activation of CD4+ T cells. 3G11 antibodies can be used to block binding of antibodies to CD3 epsilon, suggesting close proximity of these two proteins. Recently, it has been demonstrated that loss of 3G11 expression in experimental autoimmune encephalomyelitis (EAE) is associated with an anergic, regulatory T phenotype. Purified 3G11- T cells were able to suppress proliferation and cytokine production of 3G11+ T cells, and part of this effect was due to the secretion of IL-10.
3G11 Sialoganglioside Antigen Monoclonal antibody specifically detects 3G11 Sialoganglioside Antigen in Mouse, Rat samples. It is validated for Flow Cytometry.Specifications
3G11 Sialoganglioside Antigen | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.09% sodium azide; pH 7.2 | |
IgM κ | |
Affinity chromatography | |
Antibody |
eBio3G11 (SM3G11, 3G11), 3G11) | |
Flow Cytometry | |
eFluor 660 | |
Mouse | |
Mouse, Rat | |
3G11 antigen | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |
For Research Use Only.