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3-Phenylpropionyl chloride, 98%, Thermo Scientific Chemicals

Catalog Number p-7080987
28.06 GBP valid until 2024-03-29
Use promo code "21615" to get your promotional price.


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Quantity:
10 g
50 g
250 g
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To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
645-45-4
C9H9ClO
168.62
MFCD00000748
MFEILWXBDBCWKF-UHFFFAOYSA-N
3-phenylpropionyl chloride, hydrocinnamoyl chloride, benzenepropanoyl chloride, dihydrocinnamoyl chloride, hydrocinnamyl chloride, propionyl chloride, 3-phenyl, hydrocinnamoylchloride, beta-phenylpropionyl chloride, 3-phenylpropionic acid chloride, beta-phenylpropanoyl chloride
64801
3-phenylpropanoyl chloride
C1=CC=C(C=C1)CCC(=O)Cl
This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”21615” to get your promotional price
645-45-4
C9H9ClO
168.62
MFCD00000748
MFEILWXBDBCWKF-UHFFFAOYSA-N
3-phenylpropionyl chloride, hydrocinnamoyl chloride, benzenepropanoyl chloride, dihydrocinnamoyl chloride, hydrocinnamyl chloride, propionyl chloride, 3-phenyl, hydrocinnamoylchloride, beta-phenylpropionyl chloride, 3-phenylpropionic acid chloride, beta-phenylpropanoyl chloride
64801
3-phenylpropanoyl chloride
C1=CC=C(C=C1)CCC(=O)Cl

The 3-phenylpropionate (dihydrocinnamoyl) ester has been used as a protecting group in nucleoside synthesis. Used in the synthesis of 1-Phenyl-3-methyl-4-acyl-5- pyrazolones. N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane were prepared by acylation of the appropriate amine with 3-phenylpropionyl chloride followed by reduction of the resulting amide with either LiA1H4. For the preparation of the phenylacetyl (PA) and 3-phenylpropionyl (PP) derivatives, the corresponding amino acids were coupled in the usual manner with phenylacetyl chloride or 3-phenylpropionyl chloride in the presence of either NaOH(PA-LD- and DL-Pgly. 3-Phenylpropionyl chloride (4) was treated with diazomethane to give diazoketone. Allyloxy resin 12 was acylated with 3-phenylpropionyl chloride and treated with 50% TFA for 1 h followed by treatment with Pd(PPh3)4/PPh3 in solution to furnish the desired hydrox- amic acid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
The 3-phenylpropionate (dihydrocinnamoyl) ester has been used as a protecting group in nucleoside synthesis. Used in the synthesis of 1-Phenyl-3-methyl-4-acyl-5- pyrazolones. N-(3-phenyl-n-propyl)-1-phenyl-2-aminopropane were prepared by acylation of the appropriate amine with 3-phenylpropionyl chloride followed by reduction of the resulting amide with either LiA1H4. For the preparation of the phenylacetyl (PA) and 3-phenylpropionyl (PP) derivatives, the corresponding amino acids were coupled in the usual manner with phenylacetyl chloride or 3-phenylpropionyl chloride in the presence of either NaOH(PA-LD- and DL-Pgly. 3-Phenylpropionyl chloride (4) was treated with diazomethane to give diazoketone. Allyloxy resin 12 was acylated with 3-phenylpropionyl chloride and treated with 50% TFA for 1 h followed by treatment with Pd(PPh3)4/PPh3 in solution to furnish the desired hydrox- amic acid.

Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, amines, alcohols, active metals, bases, water, moisture.
TRUSTED_SUSTAINABILITY
Melting Point -7°C
Density 1.135
Boiling Point 225°C
Flash Point 108°C (226°F)
Odor Acrid
Refractive Index 1.5265
Quantity 10 g
UN Number UN3265
Beilstein 742586
Sensitivity Moisture sensitive
Solubility Information Soluble in water (reacts),and ether.
Formula Weight 168.62
Percent Purity 98%
Chemical Name or Material 3-Phenylpropionyl chloride
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