missing translation for 'onlineSavingsMsg'
Learn More

2-APB, Tocris Bioscience™

IP3 receptor antagonist. Also TRP channel modulator

Brand:  Tocris (Bio-Techne) 1224/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

 View more versions of this product

Product Code. 13468643

  • £82.32 / 10mg

Estimated Shipment date
from Supplier 25-03-2020

Please to purchase this item. Need a web account? Register with us today!


Description

Description

A functional and membrane permeable D-myo-inositol 1,4,5-trisphosphate (IP3) receptor antagonist (IC50 = 42 μM). Stimulates store-operated calcium (SOC) release at low concentrations (< 10 μM) and inhibits it at higher concentrations (up to 50 μM). Increases STIM-Orai channel conductance and limits ion selectivity. Modulator of TRP channels; blocks TRPC1, TRPC3, TRPC5, TRPC6, TRPV6, TRPM3, TRPM7, TRPM8 and TRPP2 and at higher concentrations stimulates TRPV1, TRPV2 and TRPV3. Also blocks specific gap channel subtypes.
Specifications

Chemical Identifiers

524-95-8
225.098
2-aminoethyl diphenylborinate, 2-apb, 2-aminoethoxy diphenylborane, 2-aminoethoxydiphenylborane, 2-aminoethoxydiphenylborate, 2-aminoethoxydiphenyl borate, o-2-aminoethyl diphenylborinic acid, b-2-aminoethoxy diphenylborane, 2-diphenylboryl oxy ethanamine, borinic acid, o-2-aminoethyl diphenyl
2-diphenylboranyloxyethanamine
C14H16BNO
BLZVCIGGICSWIG-UHFFFAOYSA-N
1598
B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN

Specifications

10mg
524-95-8
2-aminoethyl diphenylborinate, 2-apb, 2-aminoethoxy diphenylborane, 2-aminoethoxydiphenylborane, 2-aminoethoxydiphenylborate, 2-aminoethoxydiphenyl borate, o-2-aminoethyl diphenylborinic acid, b-2-aminoethoxy diphenylborane, 2-diphenylboryl oxy ethanamine, borinic acid, o-2-aminoethyl diphenyl
B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN
225.098
225.1
2-APB
C14H16BNO
BLZVCIGGICSWIG-UHFFFAOYSA-N
2-diphenylboranyloxyethanamine
1598
>98%
Videos
Documents