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10-DEBC hydrochloride, Tocris Bioscience™

Selective Akt/PKB inhibitor

Brand:  Tocris (Bio-Techne) 255850

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13461464

  • £475.00 / 50mg


Estimated Shipment
28-06-2018
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Description

Description

Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ∽ 2-6 μM) and induces apoptosis in rhabdomyosarcoma cells.
Specifications

Chemical Identifiers

10-DEBC hydrochloride
C20H25N2OCl·HCl
381.34
10-[4'-(N, N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride

Specifications

10-DEBC hydrochloride
>99%
C20H25N2OCl·HCl
10-[4'-(N, N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride
925681-41-0
50mg
381.34
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