missing translation for 'onlineSavingsMsg'
Learn More

10-DEBC hydrochloride, Tocris Bioscience™

Selective Akt/PKB inhibitor

Brand:  Tocris (Bio-Techne) 255850

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

 View more versions of this product

Product Code. 13461464

  • £461.52 / 50mg


Estimated Shipment
29-11-2018
Add to basket

Description

Description

Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ∽ 2-6 μM) and induces apoptosis in rhabdomyosarcoma cells.
Specifications

Chemical Identifiers

925681-41-0
381.341
10-debc hydrochloride, akt inhibitor x, 10-4′-n-diethylamino butyl-2-chlorophenoxazine, hcl, 10-4'-n,n-diethylamino butyl-2-chlorophenoxazine hydrochloride, 4-2-chlorophenoxazin-10-yl butyl diethylamine hydrochloride, 4-2-chloro-10h-phenoxazin-10-yl-n,n-diethylbutan-1-amine-hydrogen chloride 1/1
4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine;hydrochloride
C20H26Cl2N2O
SVKSJUIYYCQZEC-UHFFFAOYSA-N
16760284
CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl

Specifications

10-DEBC hydrochloride
925681-41-0
10-debc hydrochloride, akt inhibitor x, 10-4′-n-diethylamino butyl-2-chlorophenoxazine, hcl, 10-4'-n,n-diethylamino butyl-2-chlorophenoxazine hydrochloride, 4-2-chlorophenoxazin-10-yl butyl diethylamine hydrochloride, 4-2-chloro-10h-phenoxazin-10-yl-n,n-diethylbutan-1-amine-hydrogen chloride 1/1
CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl
381.341
381.34
50mg
C20H26Cl2N2O
SVKSJUIYYCQZEC-UHFFFAOYSA-N
4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine;hydrochloride
16760284
>99%
Videos