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10-DEBC hydrochloride, Tocris Bioscience™

Selective Akt/PKB inhibitor

Brand:  Tocris (Bio-Techne) 255850

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 50mg

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Product Code. 13461464

  • £475.00 / 50mg


Estimated Shipment
31-08-2018
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Description

Description

Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ∽ 2-6 μM) and induces apoptosis in rhabdomyosarcoma cells.
Specifications

Chemical Identifiers

925681-41-0
381.341
10-[4'-(N, N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride
C20H26Cl2N2O
SVKSJUIYYCQZEC-UHFFFAOYSA-N
16760284

Specifications

10-DEBC hydrochloride
>99%
C20H26Cl2N2O
SVKSJUIYYCQZEC-UHFFFAOYSA-N
4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine;hydrochloride
16760284
925681-41-0
50mg
10-[4'-(N, N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride
CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl
381.341
381.34
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