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10-DEBC hydrochloride, Tocris Bioscience™

Selective Akt/PKB inhibitor

Brand:  Tocris (Bio-Techne) 2558/10

Code : Z1

Additional Details : Weight : 0.01000kg

Quantity 10mg

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Product Code. 13451464

  • £149.94 / 10mg

Estimated Shipment date
from Supplier 01-04-2020

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Description

Description

Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ∽ 2-6 μM) and induces apoptosis in rhabdomyosarcoma cells.
Specifications

Chemical Identifiers

925681-41-0
381.341
Akt Inhibitor X, 10-4′-n-diethylamino butyl-2-chlorophenoxazine, hcl, 10-4'-n,n-diethylamino butyl-2-chlorophenoxazine hydrochloride, 4-2-chlorophenoxazin-10-yl butyl diethylamine hydrochloride, 4-2-chloro-10h-phenoxazin-10-yl-n,n-diethylbutan-1-amine-hydrogen chloride 1/1
4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine;hydrochloride
C20H26Cl2N2O
SVKSJUIYYCQZEC-UHFFFAOYSA-N
16760284
CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl

Specifications

10-DEBC hydrochloride
925681-41-0
Akt Inhibitor X, 10-4′-n-diethylamino butyl-2-chlorophenoxazine, hcl, 10-4'-n,n-diethylamino butyl-2-chlorophenoxazine hydrochloride, 4-2-chlorophenoxazin-10-yl butyl diethylamine hydrochloride, 4-2-chloro-10h-phenoxazin-10-yl-n,n-diethylbutan-1-amine-hydrogen chloride 1/1
CCN(CC)CCCCN1C2=CC=CC=C2OC3=C1C=C(C=C3)Cl.Cl
381.341
381.34
10mg
C20H26Cl2N2O
SVKSJUIYYCQZEC-UHFFFAOYSA-N
4-(2-chlorophenoxazin-10-yl)-N,N-diethylbutan-1-amine;hydrochloride
16760284
>99%
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