Production Chemicals and Services

cGMP Chemicals for industries demanding the strictest quality standards

cGMP Capabilities
mAbs
mRNA
Viral Vectors
Resources

CGMP Capabilities

cGMP Production Chemical Sourcing Service

Access all of the major cGMPchemicals your processes need. Our Production Chemical Sourcing Service enables you to consolidate cGMP chemical orders for multiple brands from various manufacturers to help maximize your resources and protect your timelines.

cGMP Distribution Service

Maintain compliance in your orders of GMP-manufactured chemicals and reduce transportation emissions by consolidating your supply chain. Our cGMP Distribution Service helps to ensure that the GMP quality of your chemical order is maintained in transit to your facility.

Assurance of Supply Service

Get the GMP-manufactured chemicals you need, when you need them, with just-in-time delivery. Our Assurance of Supply Service helps you meet growing demand so that raw materials are available and delivered to you when you need them.

Greenfield Global

Through our partnership with Greenfield Global, industries such as pharmaceuticals and biotechnology gain a unique edge by securing access to solvents (e.g. ethanol) of the highest purity for their critical applications, helping to foster innovation and precision in their research and manufacturing endeavors.

Avantor

Our access to Avantor's cGMP chemical portfolio of JT Baker and Macron Fine Chemicals helps to seamlessly connect the world of science with a vast array of high-purity products, offering a trusted avenue for sourcing quality materials.

Monoclonal Antibodies (mAbs)

Quality chemicals are essential in monoclonal antibody (mAb) workflows as they ensure the reliability and consistency of the production process, ultimately contributing to the safety and efficacy of therapeutic mAb products. High-grade chemicals play a pivotal role in maintaining product integrity and meeting regulatory standards in the pharmaceutical industry.

cGMP Chemical Sourcing Service

Access all of the major cGMP chemicals your processes need. Our Production Chemical Sourcing Service enables you to consolidate cGMP chemical orders for multiple brands from various manufacturers to help maximize your resources and protect your timelines.

Cell Culture

We can supply you with GMP-manufactured chemicals, no matter the scale or cell lines used.

Amino Acids
Biological Buffers
Carbohydrates
High Purity Water
Salts
Supplements
Minerals and Vitamins

Harvest and Collection

During harvest and collection, the right quality products can help in recovering cells, meeting desired high titer levels, and enabling accurate quantitation of residual host cell DNA.

Biological Buffers
Denaturants
Detergents
High Purity Water
Salts

Purification

Simplify your purification process with high-quality chemicals that can help improve the downstream purification of mAbs molecules.

Acids and Bases
Biological Buffers
High Purity Water
Salts
Solvents
Surfactants

Formulation / Fill & Finish

At the final step of the mAbs workflow, raw material quality is paramount. We provide drug product fill, finish, and storage chemicals like those used as excipients and active pharmaceutical ingredients (APIs) for therapy delivery.

Acids and Bases
Biological Buffers
Carbohydrates
High Purity Water
Salts

Cleaning, Sanitization & Storage

Cleaning and sterility assurance are critical elements of maintaining a processing environment focused on quality. Our CGMP portfolio offers a range of effective cleaning and preservation materials to increase column life and optimize column performance.

Acids and Bases
Cleaning Agents & Disinfectants
Denaturants
High Purity Water
Salts
Solvents

Messenger RNA (mRNA)

In mRNA workflows the significance of quality chemicals cannot be overstated, as they are critical for synthesizing and stabilizing mRNA molecules used in vaccine and therapeutic development. Maintaining high standards in chemical purity and reactivity is paramount to ensure the safety and effectiveness of mRNA-based treatments.

cGMP Chemical Sourcing Service

Access all of the major cGMP chemicals your processes need. Our Production Chemical Sourcing Service enables you to consolidate cGMP chemical orders for multiple brands from various manufacturers to help maximize your resources and protect your timelines.

Plasmid Production

Plasmids are the building blocks needed to manufacture mRNA therapeutics. Plasmid production takes place in a microbial fermentation process and we can help you source the cGMP chemicals needed to help scale production.

Acids and Bases
Amino Acids
Biological Buffers
Carbohydrates
High Purity Water
Denaturants
Salts
Solvents
Surfactants

Plasmid Purification

Achieve fast process development by ensuring a high-quality supply of your most critical chemicals, which can help with isolating, purifying, and extracting plasmid DNA.

Acids and Bases
Biological Buffers
High Purity Water
Salts

mRNA in Vitro Transcription

Chemicals play a crucial role in mRNA in vitro transcription by helping to facilitate the process and ensuring the production of high-quality mRNA molecules. cGMP chemicals may be included in the transcription reaction to enhance its efficiency and accuracy.

Acids and Bases
Biological Buffers
High Purity Water
Salts
Solvents

mRNA Purification

Simplify your purification process with high-quality chemicals that can help improve the downstream purification of mRNA molecules.

Acids and Bases
Biological Buffers
Carbohydrates
High Purity Water
Salts
Solvents

Cleaning, Sanitization and Storage

Cleaning and sterility assurance are critical elements of maintaining a processing environment focused on quality. Our cGMP portfolio offers a range of effective cleaning and preservation materials to increase column life and optimize column performance.

Acids and Bases
Biological Buffers
Chromatography Column Cleaning & Sanitization Solutions
Cleaning Agents and Disinfectants
Denaturants
Minerals and Vitamins
Salts
Solvents

Viral Vectors

Quality chemicals are of paramount importance in gene therapy workflows, particularly in the production of viral vectors, as they directly impact the vector's efficiency and safety. High-quality reagents and chemicals are essential for ensuring the precision and reliability of gene delivery, which is crucial for the success and safety of gene therapy treatments.

cGMP Chemical Sourcing Service

Access all of the major cGMP chemicals your processes need. Our Production Chemical Sourcing Service enables you to consolidate cGMP chemical orders for multiple brands from various manufacturers to help maximize your resources and protect your timelines.

Cell Culture

Using cGMP chemicals in cell culture ensures the safety, quality, and consistency of the viral vector production process. Regardless of the scale or cell lines used, we can help you access the critical high-quality chemicals your process needs.

Amino Acids
Biological Buffers
Carbohydrates
High Purity Water
Minerals and Vitamins
Salts

Virus Harvest

During virus harvest, cGMP chemicals are used to ensure the safety, purity, and potency of the viral vectors.

Biological Buffers
Denaturants
Detergents
High Purity Water
Salts

Purification

Purification of viral vectors involves the removal of cellular debris, host cell proteins, nucleic acids, and other impurities to obtain a highly purified and potent product. The use of cGMP chemicals in this step is crucial for maintaining product quality and safety.

Acids and Bases
Biological Buffers
Detergents
High Purity Water
Salts
Solvents
Surfactants

Formulation / Fill and Finish

At the final step of the viral vector workflow, raw material quality is paramount. We provide drug product fill, finish, and storage chemicals like those used as excipients and active pharmaceutical ingredients (APIs) for therapy delivery.

Acids and Bases
Biological Buffers
Carbohydrates
High Purity Water
Salts

Cleaning, Sanitization and Storage

Acids and Bases
Biological Buffers
Chromatography Column Cleaning and Sanitization Solutions
Cleaning Agents and Disinfectants
Denaturants
Minerals and Vitamins
Salts
Solvents

Helpful Resources

Timing is Everything: When to Consider cGMP

Current good manufacturing practice (cGMP) is central to drug manufacturing, requiring chemicals and other raw materials to be manufactured in accordance with specific controls and quality systems to produce therapeutics that prioritize patient safety. Explore key considerations that will guide you in making informed decisions about when to integrate cGMP materials into your manufacturing processes.

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Timing is everything: when to consider CGMP

Establishing a Resilient cGMP Chemical Supply Chain

Bioprocessors face no shortage of challenges in their supply chain operations. Materials can suddenly be in short supply, leaving companies to compete for increasingly scarce, yet vital, materials. Learn how to re-think your supply chain resiliency and considerations for strengthening operations with cGMP chemicals.

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Establishing a resilient CGMP chemical supply chain

Develop a Cost-Effective cGMP Chemical Sourcing Strategy

A sourcing strategy is the core of building a resilient supply chain. The right sourcing helps protect production schedules, which can accelerate critical milestones that bring biologics to market. This infographic provides considerations and estimated savings for cGMP chemical sourcing strategy. Learn about developing a strategy for sourcing the cGMP chemicals critical to your processes.

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Develop a cost-effective CGMP chemical sourcing strategy

Total Cost of Ownership

Your total cost of ownership (TCO) can vary depending on your business model. While the product price is an important element, analysis of the ancillary or hidden costs can have a significant impact on the overall cost of your operations. Explore how uncovering hidden costs can impact your ability to mitigate risk and optimize operational efficiencies.

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More Resources

Chemical Products and Services at a Glance

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Assurance Supply Services

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Production Chemicals and Sourcing Services

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cGMP* Distribution Services

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Production Chemicals and Services

When you are challenged to grow capacity and accelerate process scale-up during development, the decisions you face to source reliable raw materials are critical. Maintaining continuous quality and compliance in a regulated environment increases your chances of success.

Our team of technical specialists in cGMP chemical sourcing and supply chain management can help you maintain quality and prevent interruptions or delays through a suite of chemical sourcing and distribution services.

We work as an extension of your team to create a reliable chemical supply - providing business continuity to help accelerate milestone achievement and speed to market.