Invitrogen™ USP20 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA533102

Product Code. 13484769

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Orangutan, Gibbon, Rabbit (94%); Hamster (89%); Mouse, Bovine, Bat, Elephant, Panda, Horse, Pig, Opossum, Turkey, Chicken (83%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.

Specifications

• Antigen: USP20
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: USP20
• Gene Alias: 1700055M05Rik; AI467231; Deubiquitinating enzyme 20; hVDU2; KIAA1003; LSFR3A; pVHL-interacting deubiquitinating enzyme 2; ubiquitin carboxyl-terminal hydrolase 20; ubiquitin specific peptidase 20; ubiquitin specific protease 20; ubiquitin thioesterase 20; ubiquitin thiolesterase 20; ubiquitin-specific-processing protease 20; Usp20; Vdu2; VHL-interacting deubiquitinating enzyme 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10868
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: Q9Y2K6
• Gene Symbols: USP20
• Immunogen: Synthetic 18 amino acid peptide from internal region of human USP20.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Monkey
• Product Type: Antibody
• Isotype: IgG